Quinolinic Acid

Quinolinic Acid (chemical name: 2,3-Pyridinedicarboxylic acid; CAS No.: 89-00-9) is an important organic compound. Below are detailed specifications of its product characteristics and applications:  

I. Chemical and Physical Properties 
1. Chemical Structure  

A pyridine derivative with molecular formula C₇H₅NO₄.  

Contains two carboxyl groups, exhibiting acidic properties.  

2. Physical Properties  

Appearance: White prismatic crystals or crystalline powder.  

Melting Point: 188°C (decomposes at 190–195°C).  

Solubility:  

Freely soluble in water and alkaline solutions.  

Slightly soluble in ethanol.  

Insoluble in non-polar solvents (e.g., ether, benzene).  

II. Primary Applications  

1. Pharmaceutical Sector

Synthetic Intermediate: Used in producing nicotinic acid, niacinamide, nikethamide, and other pharmaceuticals.  

Neuroscience Research:  

Functions as an endogenous tryptophan metabolite.  

Antagonizes NMDA receptors to study neurodegenerative disease mechanisms.  

2. Agrochemical Sector 
Herbicide Intermediate: Key raw material for synthesizing herbicides (e.g., imazapyr, quinclorac) to control barnyard grass in paddy fields.  

Synergistic Effects: Enhances efficacy of other herbicides by disrupting plant hormone-regulating enzymes.  

3. Industrial & Analytical Applications  

Organic Synthesis Reagent: Used in preparing dyes, fragrances, and fine chemicals.  

Metal Ion Detection**: Serves as a reagent for copper ion quantification.  

III. Packaging & Storage  

Packaging: Typically 25 kg/drum (cardboard drum with polyethylene liner). Customizable upon request.  
Storage Conditions:  

Store in a cool, dry place at room temperature. 
Protect from light and moisture. 
IV. Safety & Precautions  

Toxicity: Low toxicity, but avoid direct skin contact or inhalation of dust.  

Environmental Impact:

Some derivatives (e.g., quinclorac) exhibit prolonged soil persistence; select follow-up crops cautiously.  
Note: For international procurement or regulatory compliance (e.g., REACH, GHS labeling), ensure suppliers provide SDS (Safety Data Sheet) and relevant certifications.