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P-Aminobenzoic Acid

The pure product is a white needle-like monoclinic crystal

  • Commodity name: P-Aminobenzoic Acid

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I. Basic Information  

Chemical Formula: C₇H₇NO₂ 
English Name: p-aminobenzoic acid (abbreviated as PABA)  

CAS No.: 150-13-0  

Appearance: The pure product is a white needle-like monoclinic crystal. It oxidizes and turns yellow when exposed to air or light, so commercially available products are often light brown crystals.  

Melting Point: 187–189 ℃.  

Solubility: Highly soluble in boiling water; soluble in ethanol, diethyl ether, ethyl acetate, and glacial acetic acid; slightly soluble in water and benzene; insoluble in petroleum ether.  

Acid-Base Property: Amphoteric substance, soluble in both acidic and alkaline solutions.  

II. Main Applications  

Pharmaceutical Field 
Pharmaceutical Synthesis Intermediate**: Used in the synthesis of various drugs, such as the local anesthetic procaine, which is an ester formed by p-aminobenzoic acid and diethylaminoethanol. 
Participation in Folic Acid Synthesis**: As a component of folic acid, it is crucial for cell growth and division. It can be used to synthesize blood tonics, coagulation-promoting agents, etc., relieving anemia to some extent and promoting human metabolism.  

Cosmetic Field 
Used as a sunscreen agent. Its derivative, octyl dimethylaminobenzoate, is an excellent sunscreen ingredient, commercially known as Padimate O.  

Dye Industry  

As an important intermediate for synthesizing various dyes, it is used in the production of reactive red M-80, M-10B, reactive red violet X-2R, etc., and in the preparation of cyanobenzoic acid for synthesizing the drug p-carboxybenzylamine.  

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