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Ethyl 4-Piperidinecarboxylate
Colorless to pale yellow clear liquid
- Commodity name： Ethyl 4-Piperidinecarboxylate
I. Basic Information
CAS: 1126-09-6
Molecular Formula: C₈H₁₅NO₂
Molecular Weight: 157.21
EINECS: 214-416-7
II. Physicochemical Properties
Appearance: Colorless to pale yellow clear liquid
Density: (25°C) 1.012 ± 0.02 g/cm³
Boiling Point: 98-100°C (12 mmHg)
Refractive Index: (nD²⁵) 1.458 - 1.462
Flash Point: 93°C (closed cup)
Solubility: Freely soluble in ethanol, DCM, THF; insoluble in water
III. Applications
1. Pharmaceutical Synthesis
- Kinase inhibitors: Key intermediate for Palbociclib
- Local anesthetics: Precursor for Ropivacaine synthesis
- Blood-brain barrier penetrator: CNS drug carrier (Log P=1.32)
2. Agrochemical Chemistry
Nitrogen heterocycle module for novel piperidine fungicides (e.g., Fluopipamide)
3. Advanced Material Synthesis
- Side-chain modifier for liquid crystal molecules
- Functional ligand for **Metal-Organic Frameworks (MOFs)
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Contact Information
Company Name: Ningxia Qiyan New Materials Co., Ltd
Address: Room C7, 14th Floor, Section B, Yinchuan International Trade Center, Xingqing District, Yinchuan City, Ningxia, China
Tel:0086-013909510736
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