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4-Piperidinecarboxylic acid
White to pale pink-beige powder
- Commodity name： 4-Piperidinecarboxylic acid
Keywords:
I. Basic Information
English Name: Isonipecotic acid
Synonyms: 4-Piperidinecarboxylic acid; Hexahydroisonicotinic acid
Molecular Formula: C₆H₁₁NO₂
Molecular Weight:129.16
CAS:498-94-2
EC:207-872-3
II. Physicochemical Properties
Appearance:White to pale pink-beige powder
Density: 1.1±0.1 g/cm³
Boiling Point:265.8±33.0 °C at 760 mmHg
Melting Point: ca. 254°C (decomposes)
III. Applications
(1) Pharmaceutical Synthesis Intermediate
4-Piperidinecarboxylic acid is a key building block for constructing Bioactive molecules, primarily used in:
Anticancer Drugs: As the piperidine ring structural unit in kinase inhibitors (targeting EGFR, ALK, etc.).
Central Nervous System (CNS) Drugs:As a synthetic precursor for antidepressants and analgesics (e.g., fentanyl derivatives).
Antihistamines:Core scaffold in some anti-allergic medications.
(2) Organic Synthesis Reagent
Used as a chiral ligand or catalyst component in asymmetric synthesis.
Modifies polymeric materials (e.g., polyamides) to enhance their functionality.
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Contact Information
Company Name: Ningxia Qiyan New Materials Co., Ltd
Address: Room C7, 14th Floor, Section B, Yinchuan International Trade Center, Xingqing District, Yinchuan City, Ningxia, China
Tel:0086-013909510736
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