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Guanidine hydrochloride
Used as an intermediate in pharmaceutical organic synthesis
- Commodity name： Guanidine hydrochloride
Keywords:
Other names: Guanidine hydrochloride
Chemical formula: CH6ClN3
Molecular weight: 95.53
CAS Registry Number: 50-01-1
Appearance: White or slightly yellow lumps
Applications: Used as an intermediate in the organic synthesis of pharmaceuticals. It is an important raw material for the production of sulfonamide drugs, folic acid, sulfapyrimidine, sulfamethazine, and sulfadimethoxine. In addition, it is used as a strong denaturant in experiments to extract total cellular RNA. Guanidine hydrochloride solution can dissolve proteins, leading to the destruction of cell structure and the secondary structure of nucleoproteins, causing them to dissociate from nucleic acids. RNA enzymes can be inactivated by reducing agents such as guanidine hydrochloride.
Industrial grade guanidine hydrochloride and industrial grade 60% guanidine hydrochloride aqueous solution are intermediates in the manufacture of pesticides, dyes, and other organic synthesis products. They can also be used as antistatic agents in synthetic fibers.
Project Name | Technical Indicators | ||
Industrial Grade | Liquid Guanidine Hydrochloride | Pharmaceutical Grade | |
Appearance | White crystals | Colorless transparent liquid | White crystals |
Content ≥ | 99% | 60±1 | 99.5 |
Ammonium salt ≤ | 0.5% | 0.5 | 0.05 |
Water insoluble matter ≤ | 0.1% | 0.2 | 0.02 |
Water ≤ | 0.3% | -- | 0.3 |
Ash ≤ | 0.05% | -- | 0.02 |
Water solubility test | Clear and colorless | -- | Clear and colorless |
Melting point range ℃ | 182-188 | -- | 183-188 |
Absorbance (UV wavelength 260nm) | 3.50 | -- | 0.04 |
Absorbance (UV wavelength 280nm) | 1.50 | -- | 0.02 |
PH value (4% aqueous solution) | 6.4±0.2 | 6.5～7.5 | 6.4±0.2 |
Specific gravity d420 | -- | 1.1～1.2 | -- |
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Company Name: Ningxia Qiyan New Materials Co., Ltd
Address: Room C7, 14th Floor, Section B, Yinchuan International Trade Center, Xingqing District, Yinchuan City, Ningxia, China
Tel:0086-013909510736
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